IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral Infections

IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral Infections

Interferon-induced transmembrane proteins (IFITMs) are a family of small proteins that localize in the plasma and endolysosomal membranes. IFITMs not only inhibit viral entry into host cells by interrupting the membrane fusion between viral envelope and cellular membranes, but also reduce the produc...

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Bibliographic Details
Main Authors: Xuesen Zhao, Jiarui Li, Cheryl A. Winkler, Ping An, Ju-Tao Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
host susceptibility
interferon-induced transmembrane proteins
IFITM
single nucleotide polymorphisms
viral infection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03228/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.03228/full

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