Biomedical and candidate SN P markers of chronopathologies can significantly change affinity of ТАТА -binding protein for human gene promoters

Biomedical and candidate SN P markers of chronopathologies can significantly change affinity of ТАТА -binding protein for human gene promoters

Computational analysis of millions of unannotated SNPs from the 1000 Genomes Project may speed up the search for biomedical SNP markers. We combined the analysis of SNPs in the binding sites of ТАТА - binding protein (ТВР) using a previously described W eb service (http://beehive.bionet.nsc.ru/cgi-b...

Full description

Bibliographic Details
Main Authors: D. A. Rasskazov, N. L. Podkolodnyy, O. A. Podkolodnaya, N. N. Podkolodnaya, V. V. Suslov, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2016-01-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
тата -binding protein (tbp)
твр-binding site
snp
promoter
твр-promoter affinity
statistical significance
pathology
circadian rhythm
snp marker
predictive preventive personalized medicine
Online Access:https://vavilov.elpub.ru/jour/article/view/486

Internet

https://vavilov.elpub.ru/jour/article/view/486

Similar Items