l-Arginine-Dependent Epigenetic Regulation of Interleukin-10, but Not Transforming Growth Factor-β, Production by Neonatal Regulatory T Lymphocytes

l-Arginine-Dependent Epigenetic Regulation of Interleukin-10, but Not Transforming Growth Factor-β, Production by Neonatal Regulatory T Lymphocytes

A growing number of diseases in humans, including trauma, certain cancers, and infection, are known to be associated with l-arginine deficiency. In addition, l-arginine must be supplemented by diet during pregnancy to aid fetal development. In conditions of l-arginine depletion, T cell proliferation...

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Bibliographic Details
Main Authors: Kuender D. Yang, Te-Yao Hsu, Hong-Ren Yu, Ching-Chang Tsai, Ling-Sai Chang, Hsin-Chun Huang, Hsin-Hsin Cheng, Jiu-Yao Wang, Jiunn-Ming Sheen, Ho-Chang Kuo, Kai-Sheng Hsieh, Ying-Hsien Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
l-arginine
neonate
regulatory T-cells
interleukin-10
DNA hypomethylation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00487/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00487/full

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