Interaction of Polyelectrolytes with Proteins: Quantifying the Role of Water

Abstract A theoretical model is presented for the free energy ΔGb of complex formation between a highly charged polyelectrolyte and a protein. The model introduced here comprises both the effect of released counterions and the uptake or release of water molecules during complex formation. The result...

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Bibliographic Details
Main Authors: Jacek J. Walkowiak, Matthias Ballauff
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202100661