Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals

Summary: The rapid development of mRNA-based vaccines against the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated vaccination schedules that have been extremely effective in naive individuals. While a two-dose immunization regimen with the BNT162b2 vacci...

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Main Authors: Daniel Lozano-Ojalvo, Carmen Camara, Eduardo Lopez-Granados, Pilar Nozal, Lucía del Pino-Molina, Luz Yadira Bravo-Gallego, Estela Paz-Artal, Marjorie Pion, Rafael Correa-Rocha, Alberto Ortiz, Marcos Lopez-Hoyos, Marta Erro Iribarren, Jose Portoles, Maria Pilar Rojo-Portoles, Gloria Ojeda, Isabel Cervera, Maria Gonzalez-Perez, Irene Bodega-Mayor, Maria Montes-Casado, Pilar Portoles, Mayte Perez-Olmeda, Jesus Oteo, Rodrigo Sanchez-Tarjuelo, Venu Pothula, Megan Schwarz, Manisha Brahmachary, Anthony Tanoto Tan, Nina Le Bert, Cecilia Berin, Antonio Bertoletti, Ernesto Guccione, Jordi Ochando
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721010044