Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

<p>Abstract</p> <p>Background</p> <p>Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the efficacy and safety of gene therapies. Oligomerized Pool ENgineering...

Full description

Bibliographic Details
Main Authors: Goodwin Mathew J, Dahlborg Elizabeth J, Regan Maureen R, Li Xiaohong, Thibodeau-Beganny Stacey, Foley Jonathan E, Maeder Morgan L, Reyon Deepak, Sander Jeffry D, Fu Fengli, Voytas Daniel F, Joung J, Dobbs Drena
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/543