Discovering Molecules That Regulate Efferocytosis Using Primary Human Macrophages and High Content Imaging.

Defective clearance of apoptotic cells can result in sustained inflammation and subsequent autoimmunity. Macrophages, the "professional phagocyte" of the body, are responsible for efficient, non-phlogistic, apoptotic cell clearance. Controlling phagocytosis of apoptotic cells by macrophage...

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Bibliographic Details
Main Authors: Sandra Santulli-Marotto, Alexis Gervais, Jamie Fisher, Brandy Strake, Carol Anne Ogden, Chelsea Riveley, Jill Giles-Komar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4686065?pdf=render