Immunomodulation of TLR2 and TLR4 by G2013 (alfa-L-Guluronic acid) in CVID Patients

Immunomodulation of TLR2 and TLR4 by G2013 (alfa-L-Guluronic acid) in CVID Patients

Background: Common variable immunodeficiency (CVID) is a primary immune disorder associated with hypogammaglobulinemia, recurrent infections and autoimmune diseases. CVID patients are frequently in contact with infectious pathogens leading to the activation of innate immunity through Toll-like recep...

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Bibliographic Details
Main Authors: Laleh Sharifi, Asghar Aghamohammadi, Monireh Mohsenzadegan, Nima Rezaei, Farzaneh Towfighi Zavareh, Mona Moshiri, Saied Bokaie, Anis Barati, Seyed Javad Sayedi, Gholamreza Azizi, Abbas Mirshafiey
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-07-01
Series:International Journal of Pediatrics
Subjects:
alfa-L-Guluronic acid
G2013
CVID
TLR2
TLR4
NF-B
IL-6
IL-1
Online Access:http://ijp.mums.ac.ir/article_8745_65a8faf6246728146d98f028c3b7cb29.pdf

Internet

http://ijp.mums.ac.ir/article_8745_65a8faf6246728146d98f028c3b7cb29.pdf

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