Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD

Chronic kidney disease (CKD) is a major healthcare problem with increasing prevalence in the population. CKD leads to end stage renal disease and increases the risk of cardiovascular disease. As such, it is important to study the mechanisms underlying CKD progression. To this end, an animal model wa...

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Bibliographic Details
Main Authors: Zahraa Mohammed-Ali, Gaile L. Cruz, Chao Lu, Rachel E. Carlisle, Kaitlyn E. Werner, Kjetil Ask, Jeffrey G. Dickhout
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/172302