Progesterone Attenuates Allodynia of Inflamed Temporomandibular Joint through Modulating Voltage-Gated Sodium Channel 1.7 in Trigeminal Ganglion

Background. Women with temporomandibular disorders (TMDs) experience some amelioration of pain during pregnancy. Progesterone increases dramatically and steadily during pregnancy. Sodium channel 1.7 (Nav1.7) plays a prominent role in pain perceptions, as evidenced by deletion of Nav1.7 alone leading...

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Bibliographic Details
Main Authors: Rui-Yun Bi, Xiao-Yu Zhang, Peng Zhang, Yun Ding, Ye-Hua Gan
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2020/6582586