New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission

New adenovirus-based vaccine vectors targeting Pfs25 elicit antibodies that inhibit Plasmodium falciparum transmission

Abstract Background An effective malaria transmission-blocking vaccine (TBV) would be a major advance in the current efforts to eliminate and, ultimately, eradicate malaria. Antibodies against Plasmodium falciparum surface protein, Pfs25, are known to block parasite development in the mosquito vecto...

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Bibliographic Details
Main Authors: Kathleen A. McGuire, Kazutoyo Miura, Christopher M. Wiethoff, Kim C. Williamson
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Malaria Journal
Subjects:
Malaria
P. falciparum
Transmission-blocking immunity
Pfs25
Adenovirus vaccine vectors
Online Access:http://link.springer.com/article/10.1186/s12936-017-1896-7

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http://link.springer.com/article/10.1186/s12936-017-1896-7

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