Novel Insights into Epigenetic Regulation of IL6 Pathway: In Silico Perspective on Inflammation and Cancer Relationship

IL-6 pathway is abnormally hyperactivated in several cancers triggering tumor cell growth and immune system inhibition. Along with genomic mutation, the IL6 pathway gene expression can be affected by DNA methylation, microRNAs, and post-translational modifications. Computational analysis was perform...

Full description

Bibliographic Details
Main Authors: Saverio Candido, Barbara Maria Rita Tomasello, Alessandro Lavoro, Luca Falzone, Giuseppe Gattuso, Massimo Libra
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
IL6
Online Access:https://www.mdpi.com/1422-0067/22/18/10172