Excess of Rare Missense Variants in Hearing Loss Genes in Sporadic Meniere Disease

Meniere's disease (MD) is a clinical spectrum of rare disorders characterized by vertigo attacks, associated with sensorineural hearing loss (SNHL) and tinnitus involving low to medium frequencies. Although it shows familial aggregation with incomplete phenotypic forms and variable expressivity...

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Bibliographic Details
Main Authors: Alvaro Gallego-Martinez, Teresa Requena, Pablo Roman-Naranjo, Jose A. Lopez-Escamez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00076/full