Resolving cellular systems by ultra-sensitive and economical single-cell transcriptome filtering
Summary: Single-cell transcriptomics suffer from sensitivity limits that restrict low abundance transcript identification, affects clustering and can hamper downstream analyses. Here, we describe Constellation sequencing (Constellation-Seq), a molecular transcriptome filter that delivers two orders...
Main Authors: | Andres F. Vallejo, James Davies, Amit Grover, Ching-Hsuan Tsai, Robert Jepras, Marta E. Polak, Jonathan West |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221001152 |
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