Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive

Mast cell leukemia (MCL) is a rare and aggressive disease with poor prognosis and short survival time. D816V c-KIT mutation is the most frequent molecular abnormality and plays a crucial role in the pathogenesis and development of the disease. Thus, comprehensive diagnostic investigations and molecu...

Full description

Bibliographic Details
Main Authors: Magalie Joris, Sophie Georgin-Lavialle, Marie-Olivia Chandesris, Ludovic Lhermitte, Jean-François Claisse, Danielle Canioni, Katia Hanssens, Gandhi Damaj, Olivier Hermine, Mohammed Hamidou
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2012/517546