Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population.

Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population.

Plasminogen activator inhibitor 1 (PAI-1), a major modulator of the fibrinolytic system, is an important factor in cardiovascular disease (CVD) susceptibility and severity. PAI-1 is highly heritable, but the few genes associated with it explain only a small portion of its variation. Studies of PAI-1...

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Bibliographic Details
Main Authors: Marquitta J White, Nuri M Kodaman, Reed H Harder, Folkert W Asselbergs, Douglas E Vaughan, Nancy J Brown, Jason H Moore, Scott M Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4556460?pdf=render

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http://europepmc.org/articles/PMC4556460?pdf=render

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