Calpain3 is expressed in a proteolitically active form in papillomavirus-associated urothelial tumors of the urinary bladder in cattle.

<h4>Background</h4>Calpain 3 (Capn3), also named p94, is a skeletal muscle tissue-specific protein known to be responsible for limb-girdle muscular dystrophy type 2A (LGMD2A). Recent experimental studies have hypothesized a pro-apoptotic role of Capn3 in some melanoma cell lines. So far...

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Main Authors: Sante Roperto, Roberta De Tullio, Cinzia Raso, Roberto Stifanese, Valeria Russo, Marco Gaspari, Giuseppe Borzacchiello, Monica Averna, Orlando Paciello, Gianni Cuda, Franco Roperto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20421977/?tool=EBI