Systematic Review and Meta-Analysis of Correlation of Progression-Free Survival-2 and Overall Survival in Solid Tumors

Systematic Review and Meta-Analysis of Correlation of Progression-Free Survival-2 and Overall Survival in Solid Tumors

Background: Using progression-free survival (PFS)2, time from randomization to 2nd disease progression or death, is proposed as a surrogate for overall survival (OS) in oncology clinical trials. We used published data from solid tumor trials to assess whether PFS2 and OS are correlated.Methods: A li...

Full description

Bibliographic Details
Main Authors: Simon Chowdhury, Paul Mainwaring, Liangcai Zhang, Suneel Mundle, Eneida Pollozi, Alexander Gray, Mark Wildgust
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
PFS2
OS
second disease progression
surrogate clinical endpoint
time to progression on second therapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01349/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01349/full

Similar Items