Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans.

Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans.

Ceramide and its metabolites constitute a diverse group of lipids, which play important roles as structural entities of biological membranes as well as regulators of cellular growth, differentiation, and development. The C. elegans genome comprises three ceramide synthase genes; hyl-1, hyl-2, and la...

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Bibliographic Details
Main Authors: Mai-Britt Mosbech, Rikke Kruse, Eva Bang Harvald, Anne Sofie Braun Olsen, Sandra Fernandez Gallego, Hans Kristian Hannibal-Bach, Christer S Ejsing, Nils J Færgeman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23894595/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23894595/?tool=EBI

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