Gene duplication, modularity and adaptation in the evolution of the aflatoxin gene cluster

<p>Abstract</p> <p>Background</p> <p>The biosynthesis of aflatoxin (AF) involves over 20 enzymatic reactions in a complex polyketide pathway that converts acetate and malonate to the intermediates sterigmatocystin (ST) and <it>O</it>-methylsterigmatocystin (...

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Bibliographic Details
Main Authors: Jakobek Judy L, Ramirez-Prado Jorge H, Carbone Ignazio, Horn Bruce W
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/7/111