Erythrocyte sphingosine kinase regulates intraerythrocytic development of Plasmodium falciparum

Abstract The sphingolipid pool is key regulator of vital cellular functions in Plasmodium falciparum a causative agent for deadly malaria. Erythrocytes, the host for asexual stage of Plasmodium, are major reservoir for Sphingosine-1-phosphate (S1P). Erythrocyte possesses Sphingosine kinase (SphK) th...

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Bibliographic Details
Main Authors: Raj Kumar Sah, Soumya Pati, Monika Saini, Shailja Singh
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80658-7