ProtRank: bypassing the imputation of missing values in differential expression analysis of proteomic data

Abstract Background Data from discovery proteomic and phosphoproteomic experiments typically include missing values that correspond to proteins that have not been identified in the analyzed sample. Replacing the missing values with random numbers, a process known as “imputation”, avoids apparent inf...

Full description

Bibliographic Details
Main Authors: Matúš Medo, Daniel M. Aebersold, Michaela Medová
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-3144-3