Toxic species in amyloid disorders: Oligomers or mature fibrils

Toxic species in amyloid disorders: Oligomers or mature fibrils

Protein aggregation is the hallmark of several neurodegenerative disorders. These protein aggregation (fibrillization) disorders are also known as amyloid disorders. The mechanism of protein aggregation involves conformation switch of the native protein, oligomer formation leading to protofibrils an...

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Bibliographic Details
Main Authors: Meenakshi Verma, Abhishek Vats, Vibha Taneja
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Amyloid disorders
fibrils
neurodegenerative disorders
oligomers
protein aggregation
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=2;spage=138;epage=145;aulast=Verma

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http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=2;spage=138;epage=145;aulast=Verma

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