Lung injury induced by short-term mechanical ventilation with hyperoxia and its mitigation by deferoxamine in rats

Lung injury induced by short-term mechanical ventilation with hyperoxia and its mitigation by deferoxamine in rats

Abstract Background Long-term mechanical ventilation with hyperoxia can induce lung injury. General anesthesia is associated with a very high incidence of hyperoxaemia, despite it usually lasts for a relatively short period of time. It remains unclear whether short-term mechanical ventilation with h...

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Bibliographic Details
Main Authors: Xiao-Xia Wang, Xiao-Lan Sha, Yu-Lan Li, Chun-Lan Li, Su-Heng Chen, Jing-Jing Wang, Zhengyuan Xia
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Anesthesiology
Subjects:
Hyperoxia acute lung injury
Mechanical ventilation
Deferoxamine
Lung surfactant protein
Xanthine oxidase
Glutathion reductase
Online Access:http://link.springer.com/article/10.1186/s12871-020-01089-5

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http://link.springer.com/article/10.1186/s12871-020-01089-5

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