Neural effects of propofol-induced unconsciousness and its reversal using thalamic stimulation

The specific circuit mechanisms through which anesthetics induce unconsciousness have not been completely characterized. We recorded neural activity from the frontal, parietal, and temporal cortices and thalamus while maintaining unconsciousness in non-human primates (NHPs) with the anesthetic propo...

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Bibliographic Details
Main Authors: André M Bastos, Jacob A Donoghue, Scott L Brincat, Meredith Mahnke, Jorge Yanar, Josefina Correa, Ayan S Waite, Mikael Lundqvist, Jefferson Roy, Emery N Brown, Earl K Miller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/60824