Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes

Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes

The synthesis and in vitro cytotoxicity of a series of RuII(arene) complexes with carbohydrate-derived phosphite ligands and various arene co-ligands is described. The arene ligand has a strong influence on the in vitro anticancer activity of this series of compounds, which correlates fairly well wi...

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Bibliographic Details
Main Authors: Muhammad eHanif, Samuel eMeier, Alexey eNazarov, Julie eRisse, Anton eLegin, Angela eCasini, Michael A. Jakupec, Bernhard K. Keppler, Christian G. Hartinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Chemistry
Subjects:
Carbohydrates
Anticancer activity
Bioorganometallic chemistry
Phosphorus ligands
Ruthenium arene compounds
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2013.00027/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fchem.2013.00027/full

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