Synthesis and antifungal activity of halogenated aromatic bis-γ-lactones analogous to avenaciolide

Synthesis and antifungal activity of halogenated aromatic bis-γ-lactones analogous to avenaciolide

Here we describe the total syntheses and characterization by elemental analyses, infrared and NMR spectroscopy of three new compounds analogous to avenaciolide, a bis-γ-lactone isolated from Aspergillus avenaceus that possesses antifungal activity, where the octyl group of the natural product was re...

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Bibliographic Details
Main Authors: Pedro A. Castelo-Branco, Mayura M. M. Rubinger, Leandro de C. Alves, Natalia A. Liberto, Thayane C. M. Nepel, Mariana Catrinck, Silvana Guilardi, Hudson A. Silvério, Wilson P. F. Neto, Laércio Zambolim, Dorila Piló-Veloso
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2012-01-01
Series:Química Nova
Subjects:
avenaciolide analogues
absolute structural determination
antifungal activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000500016&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000500016&lng=en&tlng=en

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