Association between HMGB1 and COPD: A Systematic Review

HMGB1 is an alarmin, a protein that warns and activates inflammation. Chronic obstructive pulmonary disease (COPD) is characterised by a progressive airflow obstruction and airway inflammation. Current anti-inflammatory therapies are poorly effective in maintaining lung function and symptoms of COPD...

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Bibliographic Details
Main Authors: Sebastiano Gangemi, Marco Casciaro, Giovanni Trapani, Sebastiano Quartuccio, Michele Navarra, Giovanni Pioggia, Egidio Imbalzano
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/164913