Study of the Biotransformation of Benfluron Using the Isolated Perfused Rat Liver

The isolated perfused rat liver method (IPRL) was used to find, isolate and identify further metabolites of Phase I and Phase II biotransformation of the potential cytostatic agent benfluron with special regard to the conjugation processes. Its pharmacokinetic profile during the perfusion was also e...

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Bibliographic Details
Main Authors: Zbyněk Svoboda, Milan Nobilis, Jaroslav Květina, Karel Lemr
Format: Article
Language:English
Published: Karolinum Press 1999-01-01
Series:Acta Medica
Subjects:
Online Access:https://actamedica.lfhk.cuni.cz/42/2/0073/