Anti-HCV RNA Aptamers Targeting the Genomic cis-Acting Replication Element

Anti-HCV RNA Aptamers Targeting the Genomic cis-Acting Replication Element

Hepatitis C virus (HCV) replication is dependent on the existence of several highly conserved functional genomic RNA domains. The cis-acting replication element (CRE), located within the 3' end of the NS5B coding region of the HCV genome, has been shown essential for efficient viral replication...

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Bibliographic Details
Main Authors: Alfredo Berzal-Herranz, Francisco J. Cueto, Eva Garmendia, Beatriz Berzal-Herranz, Soledad Marton
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Pharmaceuticals
Subjects:
aptamer selection
SELEX
RNA aptamers
anti-HCV aptamers
aptamer therapeutics
Online Access:http://www.mdpi.com/1424-8247/5/1/49/

Internet

http://www.mdpi.com/1424-8247/5/1/49/

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