Actionable gene-based classification toward precision medicine in gastric cancer

Actionable gene-based classification toward precision medicine in gastric cancer

Abstract Background Intertumoral heterogeneity represents a significant hurdle to identifying optimized targeted therapies in gastric cancer (GC). To realize precision medicine for GC patients, an actionable gene alteration-based molecular classification that directly associates GCs with targeted th...

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Bibliographic Details
Main Authors: Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Takaaki Hanyu, Takashi Ishikawa, Hitoshi Kameyama, Takashi Kobayashi, Jun Sakata, Hiroshi Yabusaki, Satoru Nakagawa, Nobuaki Sato, Yuki Hirata, Yuko Kitagawa, Toshiyuki Tanahashi, Kazuhiro Yoshida, Ryota Nakanishi, Eiji Oki, Dana Vuzman, Stephen Lyle, Kazuaki Takabe, Yiwei Ling, Shujiro Okuda, Kohei Akazawa, Toshifumi Wakai
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Genome Medicine
Subjects:
Gastric cancer
Next-generation sequencing
Gene panel
Precision medicine
Actionable gene
Online Access:http://link.springer.com/article/10.1186/s13073-017-0484-3

Internet

http://link.springer.com/article/10.1186/s13073-017-0484-3

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