The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle

The systematic bioanalytical characterization of the protein product of the <i>DMD</i> gene, which is defective in the pediatric disorder Duchenne muscular dystrophy, led to the discovery of the membrane cytoskeletal protein dystrophin. Its full-length muscle isoform Dp427-M is tightly l...

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Bibliographic Details
Main Authors: Paul Dowling, Stephen Gargan, Sandra Murphy, Margit Zweyer, Hemmen Sabir, Dieter Swandulla, Kay Ohlendieck
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/9/1/9