Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients

Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients

Emerin is an essential LEM (LAP2, Emerin, MAN1) domain protein in metazoans and an integral membrane protein associated with inner and outer nuclear membranes. Mutations in the human EMD gene coding for emerin result in the rare genetic disorder: Emery–Dreifuss muscular dystrophy type 1 (E...

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Bibliographic Details
Main Authors: Magda Dubińska-Magiera, Katarzyna Kozioł, Magdalena Machowska, Katarzyna Piekarowicz, Daria Filipczak, Ryszard Rzepecki
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
emerin
EDMD1
lamin
laminopathy
lamin A/C
LAP2β
tubulin
mitotic spindle
Online Access:http://www.mdpi.com/2073-4409/8/3/240

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http://www.mdpi.com/2073-4409/8/3/240

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