New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools

New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools

Abstract Background Ovarian cancer is the leading cause of gynecologic cancer-related death, due in part to a late diagnosis and a high rate of recurrence. Primary and acquired platinum resistance is related to a low response probability to subsequent lines of treatment and to a poor survival. There...

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Bibliographic Details
Main Authors: Sandra Muñoz-Galván, Blanca Felipe-Abrio, Miguel García-Carrasco, Julia Domínguez-Piñol, Elisa Suarez-Martinez, Eva M. Verdugo-Sivianes, Asunción Espinosa-Sánchez, Lola E. Navas, Daniel Otero-Albiol, Juan J. Marin, Manuel P. Jiménez-García, Jose M. García-Heredia, Adoración G. Quiroga, Purificacion Estevez-Garcia, Amancio Carnero
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Ovarian cancer
Cancer stem cells
Biomarkers
Therapy
Online Access:http://link.springer.com/article/10.1186/s13046-019-1245-5

Internet

http://link.springer.com/article/10.1186/s13046-019-1245-5

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