Crossing the LINE toward genomic instability: LINE-1 retrotransposition in cancer

Retrotransposons are repetitive DNA sequences that are positioned throughout the human genome. Retrotransposons are capable of copying themselves and mobilizing new copies to novel genomic locations in a process called retrotransposition. While most retrotransposon sequences in the human genome are...

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Bibliographic Details
Main Authors: Jacqueline R. Kemp, Michelle S. Longworth
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00068/full