Gene transfer and genome-wide insertional mutagenesis by retroviral transduction in fish stem cells.

Retrovirus (RV) is efficient for gene transfer and integration in dividing cells of diverse organisms. RV provides a powerful tool for insertional mutagenesis (IM) to identify and functionally analyze genes essential for normal and pathological processes. Here we report RV-mediated gene transfer and...

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Bibliographic Details
Main Authors: Qizhi Liu, Yunzhi Wang, Fan Lin, Lei Zhang, Yan Li, Ruowen Ge, Yunhan Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4451014?pdf=render