Role of Heme Oxygenase as a Modulator of Heme-Mediated Pathways

The heme oxygenase (HO) system is essential for heme and iron homeostasis and necessary for adaptation to cell stress. HO degrades heme to biliverdin (BV), carbon monoxide (CO) and ferrous iron. Although mostly beneficial, the HO reaction can also produce deleterious effects, predominantly attribute...

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Bibliographic Details
Main Authors: J. Catharina Duvigneau, Harald Esterbauer, Andrey V. Kozlov
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/8/10/475