The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design

Objective: Colchicine has been utilized safely in a variety of cardiovascular clinical conditions. Among its potential mechanisms of action is the non-selective inhibition of NLRP3 inflammasome which is thought to be a major pathophysiologic component in the clinical course of patients with COVID-19...

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Main Authors: Spyridon G. Deftereos, Gerasimos Siasos, Georgios Giannopoulos, Dimitrios A. Vrachatis, Christos Angelidis, Sotiria G. Giotaki, Panagiotis Gargalianos, Helen Giamarellou, Charalampos Gogos, Georgios Daikos, Marios Lazanas, Pagona Lagiou, Georgios Saroglou, Nikolaos Sipsas, Sotirios Tsiodras, Dimitrios Chatzigeorgiou, Nikolaos Moussas, Anastasia Kotanidou, Nikolaos Koulouris, Evangelos Oikonomou, Andreas Kaoukis, Charalampos Kossyvakis, Konstantinos Raisakis, Katerina Fountoulaki, Mihalis Comis, Dimitrios Tsiachris, Eleni Sarri, Andreas Theodorakis, Luis Martinez-Dolz, Jorge Sanz-Sánchez, Bernhard Reimers, Giulio G. Stefanini, Michael Cleman, Dimitrios Filippou, Christoforos D. Olympios, Vlasios N. Pyrgakis, John Goudevenos, George Hahalis, Theofilos M. Kolettis, Efstathios Iliodromitis, Dimitrios Tousoulis, Christodoulos Stefanadis
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Hellenic Journal of Cardiology
Subjects:
CRP
Online Access:http://www.sciencedirect.com/science/article/pii/S1109966620300610