Mixed Antimony(V) Complexes with Different Sugars to Modulate the Oral Bioavailability of Pentavalent Antimonial Drugs

Previous studies have shown that the association of the drug meglumine antimoniate (MA) with β-cyclodextrin can improve its bioavailability by the oral route. In this work, ribose and maltose were investigated for their ability to form mixed or association complexes with MA, release MA and modulate...

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Bibliographic Details
Main Authors: Weverson A. Ferreira, Arshad Islam, Aretha Priscilla S. Andrade, Flaviana R. Fernandes, Frédéric Frézard, Cynthia Demicheli
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/5/5478