Baseline Xpert MTB/RIF ct values predict sputum conversion during the intensive phase of anti-TB treatment in HIV infected patients in Kampala, Uganda: a retrospective study

Baseline Xpert MTB/RIF ct values predict sputum conversion during the intensive phase of anti-TB treatment in HIV infected patients in Kampala, Uganda: a retrospective study

Abstract Background In resource-limited settings, sputum smear conversion is used to document treatment response. Many People living with HIV (PLHIV) are smear-negative at baseline. The Xpert MTB/RIF test can indirectly measure bacterial load through cycle threshold (ct) values. This study aimed to...

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Bibliographic Details
Main Authors: Juliet Namugenyi, Joseph Musaazi, Achilles Katamba, Joan Kalyango, Emmanuel Sendaula, Andrew Kambugu, Jan Fehr, Barbara Castelnouvo, Yukari C. Manabe, Willy Ssengooba, Christine Sekaggya-Wiltshire
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Infectious Diseases
Subjects:
Mycobacterium tuberculosis
HIV
Xpert MTB/RIF
Baseline ct values
Time to positivity
Colony count
Online Access:https://doi.org/10.1186/s12879-021-06220-6

Internet

https://doi.org/10.1186/s12879-021-06220-6

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