Pannexin 1 Regulates Skeletal Muscle Regeneration by Promoting Bleb-Based Myoblast Migration and Fusion Through a Novel Lipid Based Signaling Mechanism

Pannexin 1 Regulates Skeletal Muscle Regeneration by Promoting Bleb-Based Myoblast Migration and Fusion Through a Novel Lipid Based Signaling Mechanism

Adult skeletal muscle has robust regenerative capabilities due to the presence of a resident stem cell population called satellite cells. Muscle injury leads to these normally quiescent cells becoming molecularly and metabolically activated and embarking on a program of proliferation, migration, dif...

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Bibliographic Details
Main Authors: Katia Suarez-Berumen, Henry Collins-Hooper, Anastasia Gromova, Robyn Meech, Alessandra Sacco, Phil R. Dash, Robert Mitchell, Valery I. Shestopalov, Thomas E. Woolley, Sakthivel Vaiyapuri, Ketan Patel, Helen P. Makarenkova
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Panx1
lipid signaling
myoblast migration
pannexins
blebbing
myoblast fusion
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.736813/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.736813/full

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