Structure and Absolute Configuration of 20β-Hydroxyprednisolone, a Biotransformed Product of Predinisolone by the Marine Endophytic Fungus Penicilium lapidosum

Structure and Absolute Configuration of 20β-Hydroxyprednisolone, a Biotransformed Product of Predinisolone by the Marine Endophytic Fungus Penicilium lapidosum

The anti-inflammatory drug predinisolone (1) was reduced to 20β-hydroxyprednisolone (2) by the marine endophytic fungus Penicilium lapidosum isolated from an alga. The structural elucidation of 2 was achieved by 1D- and 2D-NMR, MS, IR data. Although, 2 is a known compound previously obtained throug...

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Bibliographic Details
Main Authors: Sadia Sultan, Muhammad Zaimi bin Mohd Noor, El Hassane Anouar, Syed Adnan Ali Shah, Fatimah Salim, Rohani Rahim, Zuhra Bashir Khalifa Al Trabolsy, Jean-Frédéric Faizal Weber
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
20β-hydroxyprednisolone
endophytes
Penicilium lapidosum
DFT
TD-DFT
ECD spectra
Online Access:http://www.mdpi.com/1420-3049/19/9/13775

Internet

http://www.mdpi.com/1420-3049/19/9/13775

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