Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

Abstract Background Serum transferrin levels represent an independent predictor of mortality in patients with liver failure. Hepatocyte nuclear factor 4 alpha (HNF4α) is a master regulator of hepatocyte functions. The aim of this study was to explore whether serum transferrin reflects HNF4α activity...

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Bibliographic Details
Main Authors: Nurdan Guldiken, Josepmaria Argemi, Berivan Gurbuz, Stephen R. Atkinson, Martin Oliverius, Petr Fila, Karim Hamesch, Tony Bruns, Joaquín Cabezas, Juan J. Lozano, Jelena Mann, Sheng Cao, Philippe Mathurin, Vijay H. Shah, Christian Trautwein, Mark R. Thursz, Ramon Bataller, Pavel Strnad
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Medicine
Subjects:
End-stage liver disease
Cirrhosis
Alcoholic hepatitis
Transferrin
HNF4alpha
Online Access:https://doi.org/10.1186/s12916-021-01917-6

Internet

https://doi.org/10.1186/s12916-021-01917-6

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