Highlighting the Proteasome: Using Fluorescence to Visualize Proteasome Activity and Distribution

Proteasomes are critical proteases in the cell responsible for the turnover of many cytoplasmic and nuclear proteins. They are essential for many cellular processes and various diseases are associated with their malfunctioning. Proteasome activity depends on the nature of the catalytic subunits, as...

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Bibliographic Details
Main Authors: Jin Gan, Yves Leestemaker, Aysegul Sapmaz, Huib Ovaa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00014/full