Differential effects of short chain fatty acids on endothelial Nlrp3 inflammasome activation and neointima formation: Antioxidant action of butyrate

Short chain fatty acids (SCFAs), a family of gut microbial metabolites, have been reported to promote preservation of endothelial function and thereby exert anti-atherosclerotic action. However, the precise mechanism mediating this protective action of SCFAs remains unknown. The present study invest...

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Bibliographic Details
Main Authors: Xinxu Yuan, Lei Wang, Owais M. Bhat, Hannah Lohner, Pin-Lan Li
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718300247