Mineralocorticoid Receptor Signaling Contributes to Normal Muscle Repair After Acute Injury

Mineralocorticoid Receptor Signaling Contributes to Normal Muscle Repair After Acute Injury

Acute skeletal muscle injury is followed by a temporal response of immune cells, fibroblasts, and muscle progenitor cells within the muscle microenvironment to restore function. These same cell types are repeatedly activated in muscular dystrophy from chronic muscle injury, but eventually, the regen...

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Bibliographic Details
Main Authors: J. Spencer Hauck, Zachary M. Howard, Jeovanna Lowe, Neha Rastogi, Madison G. Pico, Sarah A. Swager, Jennifer M. Petrosino, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Federica Accornero, Jill A. Rafael-Fortney
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Physiology
Subjects:
mineralocorticoid receptor
mineralocorticoid receptor antagonist
conditional knockout mouse
spironolactone
myofiber
muscle injury
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01324/full

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https://www.frontiersin.org/article/10.3389/fphys.2019.01324/full

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