Inclusion Complexes of a New Family of Non-Ionic Amphiphilic Dendrocalix[4]arene and Poorly Water-Soluble Drugs Naproxen and Ibuprofen

Inclusion Complexes of a New Family of Non-Ionic Amphiphilic Dendrocalix[4]arene and Poorly Water-Soluble Drugs Naproxen and Ibuprofen

The inclusion complexes of a new family of nonionic amphiphilic calix[4]arenes with the anti-inflammatory hydrophobic drugs naproxen (NAP) and ibuprofen (IBP) were investigated. The effects of the alkyl chain’s length and the inner core of calix[4]arenes on the interaction of the two drugs with the...

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Bibliographic Details
Main Authors: Khalid Khan, Syed Lal Badshah, Nasir Ahmad, Haroon Ur Rashid, Yahia Mabkhot
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
amphiphilic calix[4]arene
naproxen
ibuprofen
solubility
inclusion complexes
Online Access:http://www.mdpi.com/1420-3049/22/5/783

Internet

http://www.mdpi.com/1420-3049/22/5/783

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