Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli

For many proteins, aggregation is one part of a structural equilibrium that can occur. Balancing productive aggregation versus pathogenic aggregation that leads to toxicity is critical and known to involve adenosine triphosphate (ATP) dependent action of chaperones and disaggregases. Recently a seco...

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Bibliographic Details
Main Authors: Michael H Hayes, Elizabeth H Peuchen, Norman J Dovichi, Daniel L Weeks
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
ATP
Online Access:https://elifesciences.org/articles/35224