Communication between corneal epithelial cells and trigeminal neurons is facilitated by purinergic (P2) and glutamatergic receptors.

Previously, we demonstrated that nucleotides released upon mechanical injury to corneal epithelium activate purinergic (P2) receptors resulting in mobilization of a Ca(2+) wave. However, the tissue is extensively innervated and communication between epithelium and neurons is critical and not well un...

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Bibliographic Details
Main Authors: Duane J Oswald, Albert Lee, Monique Trinidad, Cheryl Chi, Ruiyi Ren, Celeste B Rich, Vickery Trinkaus-Randall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3436752?pdf=render