Serum Fas Ligand, Serum Myostatin and Urine TGF-β1 Are Elevated in Autosomal Dominant Polycystic Kidney Disease Patients with Impaired and Preserved Renal Function

Serum Fas Ligand, Serum Myostatin and Urine TGF-β1 Are Elevated in Autosomal Dominant Polycystic Kidney Disease Patients with Impaired and Preserved Renal Function

Background/Aims: The pathophysiology of renal disease progression in autosomal dominant polycystic disease (ADPKD) is largely unknown. Recent evidence suggests microvascular dysfunction leading to renal ischemia, as an additional pathway for renal function decline. This study examined the levels of...

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Bibliographic Details
Main Authors: Vassilios Raptis, Constantinos Bakogiannis, Charalampos Loutradis, Afroditi K. Boutou, Athanasios Sioulis, Elias Balaskas, Pantelis Zebekakis, Pantelis A. Sarafidis
Format: Article
Language:English
Published: Karger Publishers 2018-05-01
Series:Kidney & Blood Pressure Research
Subjects:
Fibrosis
Apoptosis
Endothelial dysfunction
Chronic kidney disease
Online Access:https://www.karger.com/Article/FullText/489911

Internet

https://www.karger.com/Article/FullText/489911

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